HARMONY TEST SOFTWARE
HARMONY TEST FREE

To be eligible for the Harmony blood test, patients MUST BE at least 10 weeks’ gestational age. We are unable to provide any refunds in these circumstances. Missed miscarriages commonly occur before 12 weeks gestation and you may not want the heartache of having a result from the harmony test if this has occurred. We would always encourage you to have an ultrasound scan immediately prior to the harmony blood test. * = £15 Surcharge for Weekend appointment (Includes discussion with your doctor and signing your consent forms) We have looked through every single NIPT test available and feel that the Harmony test has the best credentials to be offered to our patients. Our Doctors think the Harmony test is the best NIPT test: The test is also capable of testing for the gender of your child, if required. As this is a blood test from the pregnant mother, there is no risk of harm to the foetus. This occurs when there are 3 copies of a particular chromosome instead of the usual 2. From this, it will give one of the most accurate screening approaches to estimating the risk of a foetus having a common chromosomal abnormality, called a Trisomy.

HARMONY TEST FREE

The Harmony Blood test (Non Invasive Prenatal Testing) analyses cell free DNA circulating in a pregnant mother’s blood. The quality is determined by the presence of 10 DNA fragments on 10 different chromosomes.Īfter WGA single cell STR analysis or DNA copy number variation analysis is performed to detect chromosomal abnormalities and genetic disorders.Harmony Test London with NO NEED to pay for an Ultrasound as well if you don’t need one. The quality of the WGA product is determined using V圜AP’s WGA control mix.

V圜AP has validated protocols based on AMPLI-1 and REPLI-G whole genome amplification (WGA). Our workfow to isolate fetal cells is compatible with most commercial sequence technologies. Furthermore the PCR tube location (A0, A1, A2,…) and an image of the microwell bottom before and after punching. It shows the microwell ID (number), and several images of the cell in different fluorescent channels.

Each horizontal row belongs to a single fetal cell.

HARMONY TEST SOFTWARE

The Puncher software screenshot below displays punched trophoblast. Isolate single trophoblasts with the Puncher systemĪfter the trophobalsts are identified these are isolated and transferred to a PCR plate or PCR tube using the Puncher system. Currently our workflow is based on Rosettesep enrichment. The enriched cells are labelled with the fluorescent labels, DAPI, CK-PE and CD45-APC, to indentify the trophoblast cells. This low frequency of appaerance requires to pre-enrich the trophoblasts cells. CNV analysis of fetal cellsĪ tube of maternal blood of 10ml contains around 10-15 fetal cells. Single fetal throphoblast cells can be genetically analysed for example copy variation analysis (CNV). With the V圜AP work flow a cell based NIPT becomes reality. Prenatal detection of chromosome abnormalities has been offered for more than 40 years, first by amniocentesis in the early 1970s and additionally by chorionic villus sampling (CVS) in the early 1980s. V圜AP offers a solution to isolate fetal trophoblast cells from maternal blood for genetic analysis.

The ability to isolate fetal cells and fetal DNA from maternal blood during pregnancy has opened up exciting opportunities for improved noninvasive prenatal testing (NIPT).